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IMG 7289 CTP 201 was a global open label Phase 2b study of bomedemstat IMG 7289 MK 3543 taken once daily for 24 weeks in patients with ET resistant to or intolerant of at least one standard treatment NCT04254978

Lysine specific demethylase 1 LSD1 is a histone demethylase critical for self renewal potential of malignant stem cells and progenitor maturation Bomedemstat is an oral LSD1 inhibitor clinically active in patients with MPNs IMG 7289 CTP 102 is a global open label Phase 2 study evaluating bomedemstat dosed in MF patients NCT03136185

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IMG 7289 Tracey Howard Flickr

img-7289-tracey-howard-flickr
IMG 7289 Tracey Howard Flickr


IMG 7289 CTP 201 is an ongoing global open label Phase 2b study of bomedemstat taken QD for 24 weeks in patients with ET who are resistant intolerant to at least one standard treatment NCT04254978

Aims IMG 7289 CTP 102 is an ongoing global open label Phase 2 study evaluating bomedemstat dosed QD in MF patients NCT03136185 Key eligibility criteria include patients intolerant refractory resistant or inadequately controlled by approved therapy and platelet count 100 x 109 L Key objectives are safety and reduction of spleen

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IMG 7289

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Bomedemstat also known as IMG 7289 Figure 8 Hiatt et al 2022 is an oral small molecule irreversible LSD1 inhibitor IC 50 56 8 nM developed by Imago BioSciences in clinical trials for myeloid related malignancies Table 1

IMG 7289 CTP 102 is an ongoing multi national open label 24 week Phase 2 study of IMG 7289 taken once daily in MF patients resistant to all approved therapies Key objectives are safety and reduction a in spleen volume

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IMG 7289


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Check more sample of Img 7289 below


IMG 7289 LewisTalkWA

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Img 7289 209112166


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IMG 7289 Angie Six Flickr


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IMG 7289 Dreesch7


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IMG 7289 JPG Picture February 2015


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IMG 7289 Daoan Flickr


img-7289-daoan-flickr

 IMG 7289 Ferreting Out The Fun
A Phase 2 Study Of The LSD1 Inhibitor Bomedemstat IMG 7289

https://ashpublications.org/blood/article/140...
Lysine specific demethylase 1 LSD1 is a histone demethylase critical for self renewal potential of malignant stem cells and progenitor maturation Bomedemstat is an oral LSD1 inhibitor clinically active in patients with MPNs IMG 7289 CTP 102 is a global open label Phase 2 study evaluating bomedemstat dosed in MF patients NCT03136185

 IMG 7289 Tracey Howard Flickr
A Phase 2 Study Of The LSD1 Inhibitor Bomedemstat IMG 7289

https://ashpublications.org/blood/article/140/Supplement 1/1784/493220
IMG 7289 CTP 201 is a global open label Phase 2b study of bomedemstat taken once daily for 24 weeks in patients with ET who are resistant to or intolerant of at least one SOC treatment NCT04254978

Lysine specific demethylase 1 LSD1 is a histone demethylase critical for self renewal potential of malignant stem cells and progenitor maturation Bomedemstat is an oral LSD1 inhibitor clinically active in patients with MPNs IMG 7289 CTP 102 is a global open label Phase 2 study evaluating bomedemstat dosed in MF patients NCT03136185

IMG 7289 CTP 201 is a global open label Phase 2b study of bomedemstat taken once daily for 24 weeks in patients with ET who are resistant to or intolerant of at least one SOC treatment NCT04254978

img-7289-dreesch7

IMG 7289 Dreesch7

img-7289-209112166

Img 7289 209112166

img-7289-jpg-picture-february-2015

IMG 7289 JPG Picture February 2015

img-7289-daoan-flickr

IMG 7289 Daoan Flickr

img-7289-il-aasgutenil-aasguten

IMG 7289 IL AasgutenIL Aasguten

img-7289-209112166

IMG 7289 Blog Di Viaggi

img-7289-blog-di-viaggi

IMG 7289 Blog Di Viaggi

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IMG 7289 GiraGira